Structural, Synaptic, and Epigenetic Dynamics of Enduring Memories.

In a review article published in the journal Neural Plasticity earlier this year, Ossama Khalaf, PhD student in the lab or neuroepigenetics, and Johannes Gräff, assistant professor at the Brain Mind Institute, outline three essential mechanisms that might explain the extreme stability and near indelibility of long-term traumatic memories: Structural, synaptic and epigenetic modifications in the brain. One research axis in the lab of neuroepigenetics is focused on better understanding how to attenuate long-term traumata, and thus a better insight into the persistence of such memories is of key importance to tackle this question.